The neurobiology of bipolar disorder.

Construct Validity and Reliability of a Bipolar Disorder Symptoms Inventory (BDSI)

Background: In order to assess the symptoms of bipolar disorder and to construct an inventory, this study was performed on 108 people from two sample groups (53 non-clinical participants) (55 participants with bipolar disorder) who were selected by a purposive sampling method. Methods: In order to evaluate the reliability of this 74-item of the inventory, the method of internal consistency and ...

Differences and Similarities in Attentional Bias between Patients with Bipolar II Disorder and Borderline Personality Disorder

Background and purpose: The boundary between bipolar disorder and borderline personality disorder has always been a matter of debate. Despite the importance of this issue, only a few studies have directly compared these two groups. The main purpose of this study was to compare the cognitive profile of patients with bipolar disorder and borderline personality disorder in terms of attentional bia...

Mitochondrial dysfunction in bipolar disorder: from 31P-magnetic resonance spectroscopic findings to their molecular mechanisms.

Olfactory sulcus morphology in established bipolar affective disorder.

This MRI study examined the morphology of the olfactory sulcus, a potential marker of early neurodevelopment in 26 patients with bipolar I disorder and 24 matched controls. Bipolar patients had significantly shallower olfactory sulci bilaterally compared to controls, suggesting that neurodevelopmental abnormalities contribute to the neurobiology of bipolar disorder.

Evaluation of the effective factors on Bipolar I Disorder frequent recurrence in a 5 years longitudinal study using generalized estimation equations method

Background and Purpose: Patients with Bipolar I Disorder recurrence experiences mood variation between manic and depression during the time. Hence, that is need to the longitudinal study on Bipolar Disorder patients. This study aims to evaluate the effective factors on Bipolar I Disorder frequent recurrence in 5 years longitudinal study using generalized estimation equations (GEE) m...